Greetings Claudia,
there are lots of genre options out there, gurps is pretty decent for handling them, i prefer savage worlds myself, for non fantasy stuff, Call of Cthulhu is my go to horror, the hero system was also very flexible as an option
I use the dungeon tiles and the stuff that piazo puts out. I lay out whats going to used in the game, cover that with a clear acrylic sheet and a vinyl matt above till it comes to the reveal